Don't let the door hit you on the way out
Dec. 28th, 2025 08:47 pm2025 but pictured in gingerbread. Amazing art.
[I]n the trenches of trans health care, there is a growing idea that pushes back against the “one true gender for each individual” framing altogether—one that could allow us to resolve the bitterly divisive culture war over the psychological and medical care of transgender children. What if, instead of viewing gender as a fixed trait, we started to think of it as something that could evolve over the course of a lifetime? Or if detransitioning wasn’t considered a sign of failure and was instead regarded as a natural and healthy part of the gender development process?
Taking the bus might not feel as sexy as driving a Mustang, but this is the role of the passenger princess: to romanticize the blue glow of the late-night buses; to celebrate the serendipitous conversations with poets, former MMA fighters and sommeliers doubling as rideshare drivers; to enjoy the intimacy and trust of a loved one driving you somewhere you need to go. Let’s keep the city yours and mine.
In healthy human community, the kind that so many people say they want, and the kind study after study suggests people living in Western countries feel is missing in their lives, human beings are often in community with people with whom we aren’t individually or personally close, but who nonetheless form part of the larger circle of human bonds that forms the anchor and soilbed of our belonging.
Collective care refers to seeing members’ well-being – particularly their emotional health – as a shared responsibility of the group rather than the lone task of an individual. It means that a group commits to addressing interlocking oppressions and reasons for deteriorating well-being within the group while also combatting oppression in society at large.
Gladys West and her husband Ira were both mathematicians at Dahlgren Naval Base, then called Dahlgren Naval Proving Ground. West was hired in 1956. Her extraordinary contributions to the geodetic modeling of the earth became the foundation for the Global Positioning System (GPS). But few knew how much this Black woman changed the way we navigate.
There is a real rot at the core of many of our institutions – and certainly at the core of those powerful players operating within and adjacent to them. "Artificial intelligence" emerges from this rot. It cannot be a bulwark against it.
Every time a translator takes a book and puts it in their own words, they are interpreting the material slightly differently. What we found was that ChatGPT Plus couldn’t do that. It could regurgitate or transcribe, but it couldn’t achieve the nuance to count as its own interpretation of a study.
I think that’s because ChatGPT Plus isn’t in society — it doesn’t interact with the world. It’s predictive, but it’s not distilling or conceptualizing what matters most to a human audience, or the value that we place in narratives that are ingrained in our society. [...]
Now, after this experiment, we’re very against using it. After a year of data, we know it can’t meet our standards. If we ever did plan to use it, we’d have to implement super rigorous fact-checking, because we don’t want to lose reporters’ trust.
Creating a pattern requires considering the entire work; each step has to fit with and work with all the others. Blindly selecting the next step without that consideration will, more often than not, fail. This is especially true since AI can’t “test” the pattern after writing it, which is a big part of what humans do. [...]
However, the best and simplest advice is to buy from patternmakers that you trust. If you know someone who is a human making high-quality patterns, turn to them first. Rewarding known human creators rather than chasing the cheapest pattern is the best way to avoid buying AI slop.
No matter how well “AI” works, it has some deeply fundamental problems, that won’t go away with technical progress. I’d even go as far and say they are intentional.
Black and white thinking is a trauma response that is important to break down for our overall happiness and wellbeing. When we are not feeling safe, it’s easy to slide into rigid thought patterns such as everything is either good or bad, friend or enemy, kind or mean, awesome or awful etc. The reality is things are rarely ever all one or the other, and as we break down binary ways of thinking we allow more space for connection and collaboration to move forward in our lives.
When I was twelve, I used to roller-skate in circles for hours. I was at another new school, the odd man out, bullied by my desk mate. My problems were too complex and modern to explain. So I skated across parking lots, breezeways, and sidewalks, I listened to the vibration of my wheels on brick, I learned the names of flowers, I put deserted paths to use. I decided for myself each curve I took, and by the time I rolled home, I felt lighter. One Saturday, a friend invited me to roller-skate in the park. I can still picture her in green protective knee pads, flying past. I couldn’t catch up, I had no technique. There existed another scale to evaluate roller skating, beyond joy, and as Rollerbladers and cyclists overtook me, it eclipsed my own. Soon after, I stopped skating.
It was amazing to me to get to graduate school and to discover that I was a Southerner, and to discover that there was this idea that once all the Black [Southern] people left for the Great Migration, apparently we just didn’t even exist anymore, despite the inconvenient fact of the whole civil rights movement. So I had a bone to pick, and I just continued picking it.
"You have an emotional response to sound," says Prof Clark. Sound is detected by the ear and passed onto the brain and one region – the amygdala – performs the emotional assessment. This is part of the body's fight-or-flight response that has evolved to help us react quickly to the sounds like a predator crashing through the bushes. "So your heart rate goes up, your nervous system starts to kick in and you release stress hormones," Prof Clark tells me.
Through analysis of immune cells, biomarkers in the blood and RNA sequencing, they identified a distinct immune signature in female versus male patients.
They found evidence of “gut leakiness” in the women patients, including elevated blood levels of intestinal fatty acid binding protein, lipopolysaccharide, and the soluble protein CD14 — all signs of gut inflammation that can then trigger further systemic inflammation once they reach the circulatory system.
There's noise, so much noise, but there's also signal and the signal was that they were here that they were everywhere. Smash and grab jobs happening across the city nearly simultaneously. But the things being stolen aren't jewels, they're lives. Off streets, from yards. One roofer plucked off a ladder. A landscaper thrown to the ground, tackled by a half-dozen men in camo with weapons. Sixteen people on this day. Sixteen people disappeared, from just the northern side of the city and suburbs. More across the entire city.
Love Life Acknowledgement (Abridged Version)
We acknowledge that in service to our beloved city of Oakland, and all its citizens, adhering to the city of Oakland's official motto, "Oakland Love Life" we enter into this space committed to embody love as our guiding principle.
We acknowledge Love Life as our motto as we denounce violence in all forms and the conditions that create it.
We acknowledge that when we demonstrate love, we also exhibit respect and kindness towards each other.
We commit to acts of love as an intentional force to generate tangible solutions, in regards to all of our actions.
We recognize as leaders, we must set an example and precedent for those in community who have entrusted us with these duties.
We welcome and appreciate all contributions to this space, and even when expressing disagreement, we request that we lead with love in your heart.
We seek to find common ground, and tangible solutions that demonstrate love for our city, its residents, and all constituents.
We acknowledge that when we lead with love we are able to uplift a thriving city rooted in equity, equality, justice, inclusion, and opportunity for all.
We commit to the action of "Love Life" as our motto and mantra.
right in your browser, where the address reads https://www.wired.com/2004/03/honey-i-shrunk-the-url/ stick right in front of it archive.ph/ making the full link http://archive.ph/https://www.wired.com/2004/03/honey-i-shrunk-the-url/
TGD individuals demonstrated a significantly higher prevalence of hEDS and HSD than cisgender individuals (OR: 18.45). The prevalence among TGD individuals assigned female at birth was 2.62%, and among those assigned male at birth, 1.00%, compared with 0.16% and 0.04% in cisgender females and males, respectively. Hormone therapy status was not associated with significant differences in prevalence.
The researchers found 35 blood proteins that were different in people with hEDS compared to those without. Most of these changes were in proteins linked to the immune system, blood clotting, blood pressure, and inflammation. The largest group of changes involved the complement system, which helps the body fight infection and control inflammation.
ME/CFS is no longer viewed as a complete “mystery.” A simple PubMed search reveals hundreds of biomedical studies showing measurable differences between people with ME/CFS and healthy controls.
COVID is most often transmitted via the air, not droplets like we thought early in the pandemic. As such: Fresh air will be your easiest and most effective option, assuming climate safety. Even a slightly open window will be MUCH better than closed windows.
If you have had Covid-19 (tested or not), and are getting to a month or two on and still feel like you’ve been hit by a bus, please, for the love of God, rest.
CONVALESCE.
The new treatment is a type of gene therapy given during 12 to 18 hours of delicate brain surgery. [...] "We never in our wildest dreams would have expected a 75% slowing of clinical progression," she said.
We estimate that the average Tropical Cyclone generates 7,000–11,000 excess deaths, exceeding the average of 24 immediate deaths reported in government statistics6,7. Tracking the effects of 501 historical storms, we compute that the TC climate of CONUS imposes an undocumented mortality burden that explains a substantial fraction of the higher mortality rates along the Atlantic coast and is equal to roughly 3.2–5.1% of all deaths.
a lone telephone booth in what is now the Mojave National Preserve in California. It attracted online attention in 1997 for its unusual location – it was located at the intersection of two dirt roads in a remote part of the Mojave Desert, 12 miles (19 km) from the nearest paved road (Interstate 15 to the northeast, Kelbaker Road to the southwest) and miles from any buildings.
[I]n the western Mojave desert of California I passed in quick succession three vast renewable energy sites: the first was three solar concentrator power plants, the kind where rings of mirrors reflect sun onto a central tower, which I think is now an outdated model, but it was striking to see the literally dazzling array; the second was a big field of solar panels around the town of Mojave t hat appeared to be tipping toward the setting sun; and then a long array of wind turbines just before the desert ends as the road heads uphill into Tehachapi
Now, you can go to Península Valdés and find that the whale population there is growing year after year, people can see them from their windows. In Iberá, where yaguaretés were extinct for over 70 years, there's now a population of 35 and growing, after being reintroduced just five years ago. As for rainforests?